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Effect of combinations of antioxidants on oxygen radical‐induced sister chromatid exchanges
Author(s) -
Weitberg Alan B.
Publication year - 1987
Publication title -
clinical genetics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.543
H-Index - 102
eISSN - 1399-0004
pISSN - 0009-9163
DOI - 10.1111/j.1399-0004.1987.tb03336.x
Subject(s) - sister chromatids , chinese hamster ovary cell , sister chromatid exchange , chemistry , oxygen , hamster , antioxidant , vitamin e , biochemistry , genetics , biology , dna , microbiology and biotechnology , gene , organic chemistry , receptor , chromosome
Oxygen radical scavengers significantly reduced the number of sister chromatid exchanges in Chinese hamster ovary cells exposed to an oxygen radical‐generating enzyme System. When vitamin E was combined with these antioxidants, no genetic toxicity was observed.