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Supernumary marker chromosomes in a mentally retarded population identified as in vdup(15)
Author(s) -
KIRKILIONIS A. J.,
SERGOVICH F. R.
Publication year - 1987
Publication title -
clinical genetics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.543
H-Index - 102
eISSN - 1399-0004
pISSN - 0009-9163
DOI - 10.1111/j.1399-0004.1987.tb02837.x
Subject(s) - dup , mentally retarded , etiology , down syndrome , population , genetics , biology , psychology , psychiatry , medicine , developmental psychology , gene , gene duplication , environmental health
Bisattelited supernumary chromosomes, identified as inv dup(15)s, were detected at a prevalence of 8/1000 among institutionalized, mentally retarded (non‐Down syndrome) males. This finding suggests that the inv dup(15) contributes significantly to the etiology of mental retardation among institutionalized individuals.