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Cytogenetic analysis in 100 spontaneous abortions in North‐East Scotland
Author(s) -
Procter Susan E.,
Watt Jessie L.,
Gray Elizabeth S.
Publication year - 1986
Publication title -
clinical genetics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.543
H-Index - 102
eISSN - 1399-0004
pISSN - 0009-9163
DOI - 10.1111/j.1399-0004.1986.tb01230.x
Subject(s) - trisomy , incidence (geometry) , induced abortions , aneuploidy , obstetrics , gynecology , abortion , first trimester , chorionic villus sampling , down syndrome , pregnancy , demography , biology , medicine , genetics , gestation , research methodology , population , family planning , chromosome , physics , sociology , gene , optics
The results of an extremely detailed cytogenetic analysis on 100 spontaneous abortions occurring in the Aberdeen area over a 3 year period is presented. A comparison with other published series reveals that there is a higher culture success rate (93%) accompanied by a lower incidence of trisomy and a higher incidence of triploidy, although the percentage of chromosomally abnormal foetuses in first trimester abortions is comparable with other studies. However, these apparent discrepancies can largely be explained on the basis of gestational age and sampling variation.