Premium
Distal 11q monosomy. The typical 11q monosomy syndrome is due to deletion of subband 11q24.1
Author(s) -
Fryns J. P.,
Kleczkowska A.,
Buttiens M.,
Marien P.,
Berghe H. VAN DEN
Publication year - 1986
Publication title -
clinical genetics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.543
H-Index - 102
eISSN - 1399-0004
pISSN - 0009-9163
DOI - 10.1111/j.1399-0004.1986.tb00605.x
Subject(s) - monosomy , breakpoint , phenotype , genetics , biology , karyotype , chromosome , gene
In this paper we describe two new patients with distal 11q monosomy and precisely localize breakpoints using high resolution banding techniques. The findings in these two patients further contribute to the precise localization of the crucial band for 11q monosomy syndrome as being at 11 q24.1. A very distal 11 q24.2 deletion in the second patient resulted in a completely different phenotype.