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Chromosomal mosaicism and maternal cell contamination in chorionic villi cultures
Author(s) -
Schulze Bernt,
Miller Konstantin
Publication year - 1986
Publication title -
clinical genetics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.543
H-Index - 102
eISSN - 1399-0004
pISSN - 0009-9163
DOI - 10.1111/j.1399-0004.1986.tb00602.x
Subject(s) - chorionic villi , chorionic villus sampling , karyotype , biology , andrology , amniotic fluid , fetus , chromosome , prenatal diagnosis , in utero , pregnancy , genetics , medicine , gene
In a series of 110 chromosome analyses, after chorionic villus sampling, mosaics were found in 3 out of 106 long term cultures. In all 3 cases, subsequent amniotic fluid cell cultures showed normal karyotypes. Maternal cell contamination was encountered in one long term culture derived from carefully dissected chorionic villi.