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Growth curves for height in Noonan syndrome
Author(s) -
Witt David R.,
Keena Beth A.,
Hall Judith G.,
Allanson Judith E.
Publication year - 1986
Publication title -
clinical genetics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.543
H-Index - 102
eISSN - 1399-0004
pISSN - 0009-9163
DOI - 10.1111/j.1399-0004.1986.tb00587.x
Subject(s) - noonan syndrome , short stature , growth curve (statistics) , growth retardation , body height , medicine , pediatrics , endocrinology , biology , mathematics , genetics , statistics , body weight , pregnancy
Growth retardation is a relatively consistent feature of Noonan syndrome but a standardized growth curve for height has never been calculated. Analysis of retrospective growth data on 112 patients with Noonan syndrome has permitted the establishment of preliminary reference growth standards for height for males and females. The results confirm the clinical impression that short stature among this group of patients occurs uniformly and is independent of chronological age. Various factors which may modify this are considered.