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Segregation analysis of brown oculocutaneous albinism
Author(s) -
King Richard A.,
Rich Stephen S.
Publication year - 1986
Publication title -
clinical genetics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.543
H-Index - 102
eISSN - 1399-0004
pISSN - 0009-9163
DOI - 10.1111/j.1399-0004.1986.tb00550.x
Subject(s) - oculocutaneous albinism , albinism , genetics , biology
The segregation of brown (type IV) oculocutaneous albinism was analyzed in 18 Nigerian families. Analysis using the POINTER program showed that this type of oculocutaneous albinism was inherited in an autosomal recessive pattern, with an estimated gene frequency of 0.025 ± 0.007 in this population. The enzyme defect responsible for brown oculocutaneous albinism is unknown.