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DNA polymorphism of the RC8 probe on the X‐chromosome: Identification of a new DNA variant with the Taql enzyme
Author(s) -
Børresen A.L.,
Jordfald A.B.,
Berg K.
Publication year - 1985
Publication title -
clinical genetics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.543
H-Index - 102
eISSN - 1399-0004
pISSN - 0009-9163
DOI - 10.1111/j.1399-0004.1985.tb02285.x
Subject(s) - genetics , restriction fragment length polymorphism , biology , locus (genetics) , mendelian inheritance , restriction enzyme , x chromosome , microbiology and biotechnology , dna , population , gene , restriction fragment , duchenne muscular dystrophy , genotype , demography , sociology
Restriction fragment length polymorphisms detectable with the RC8 probe, a probe for an area located on the short arm of the X‐chromosome, and loosely linked to the locus for Duchenne muscular dystrophy, have been studied in a Norwegian population. With the Taql enzyme three variants were observed. The gene frequencies of the previously detected variants were 0.867 and 0.082, respectively, and the frequency of a new variant was 0.051. Family studies confirmed Mendelian inheritance of the variants.