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Effect of folic acid treatment in the fragile X syndrome
Author(s) -
Gustavson KarlHenrik,
Dahlbom Kate,
Flood Anders,
Holmgren Gösta,
Blomquist Hans K→son,
Sanner Gunnar
Publication year - 1985
Publication title -
clinical genetics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.543
H-Index - 102
eISSN - 1399-0004
pISSN - 0009-9163
DOI - 10.1111/j.1399-0004.1985.tb00232.x
Subject(s) - fragile x syndrome , folic acid , fragile x , medicine , endocrinology , pediatrics , biology , genetics , psychiatry , gene
The effect of folic acid intake on the frequency of fragile X positive cells and some behavioural characteristics were evaluated in 5 boys and 4 adult males with the fragile X syndrome. The expression of fragile X was nullified in 6 and decreased in 3 of the 9 patients. Behavioural and motor ability were considered to have improved in 4 of the 5 boys but not in the 4 adults with fragile X syndrome.