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Autosomal recessive inheritance of juvenile periodontitis: test of a hypothesis
Author(s) -
Saxén Leena,
Nevanlinna H. R.
Publication year - 1984
Publication title -
clinical genetics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.543
H-Index - 102
eISSN - 1399-0004
pISSN - 0009-9163
DOI - 10.1111/j.1399-0004.1984.tb01999.x
Subject(s) - heredity , juvenile , inheritance (genetic algorithm) , biology , genetics , multifactorial inheritance , autosomal recessive inheritance , disease , medicine , genotype , gene , single nucleotide polymorphism
The heredity of juvenile periodontitis was studied in a series of 30 families. None of the 60 parents showed any sign of this disease. Of the 52 siblings, nine in seven families were affected. The calculated genetic ratio concurred with the hypothesis of autosomal recessive inheritance based on the results of an earlier study of 31 families (Saxén 1980).