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Mosaic tetrasomy 21 in a male child
Author(s) -
Kwee M. L.,
Barth P. G.,
Arwert F.,
Madan K.
Publication year - 1984
Publication title -
clinical genetics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.543
H-Index - 102
eISSN - 1399-0004
pISSN - 0009-9163
DOI - 10.1111/j.1399-0004.1984.tb00805.x
Subject(s) - tetrasomy , mosaic , genetics , chromosome , biology , x chromosome , karyotype , gene , history , archaeology
We report a three‐year‐old male child with dysmorphy, severe mental retardation and a mosaic tetrasomy 21 caused by an extra F‐like chromosome composed of two long arms of chromosome 21. We have compared this unusual case with two other similar published case reports. Hypotheses to account for the origin of the abnormal chromosome and the mosaicism are presented and discussed.