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Do the MN and Jk systems influence environmental variability in serum lipid levels?
Author(s) -
Martin N. G.,
Rowell D. M.,
Whitfield J. B.
Publication year - 1983
Publication title -
clinical genetics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.543
H-Index - 102
eISSN - 1399-0004
pISSN - 0009-9163
DOI - 10.1111/j.1399-0004.1983.tb00061.x
Subject(s) - triglyceride , cholesterol , medicine , endocrinology , total cholesterol , serum cholesterol , chemistry , biology
Significant heterogeneity in the distribution of within pair variances of serum total cholesterol, HDL cholesterol, non HDL cholesterol and triglyceride levels has been found in one or both of two samples of MZ twins. We have found some support for the observation of Magnus et al. (1981) that M˜ pairs have greater environmental variability in cholesterol levels than M +pairs and weaker evidence that Jka+pairs are more variable than Jk a‐ pairs. However, these effects appear to be more striking on triglyceride levels. The low power of the variance ratio test is advanced as a possible reason for the inconsistencies in these findings.