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Chromosomal studies in healthy blood donors with IgA deficiency
Author(s) -
Herrmann R. P.,
Chipper L.,
Bell S.
Publication year - 1982
Publication title -
clinical genetics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.543
H-Index - 102
eISSN - 1399-0004
pISSN - 0009-9163
DOI - 10.1111/j.1399-0004.1982.tb01439.x
Subject(s) - iga deficiency , genetics , medicine , biology , immunology , antibody
Chromosomal analysis was performed in 70 asymptomatic blood donors found over a 5‐year period in a large screening programme to be IgA deficient. No abnormalities were found in any of these individuals in relation to their chromosomal constitution and, in particular, chromosome 18 was normal in all individuals. A further 10 symptomatic individuals with IgA deficiency also showed a normal chromosomal constitution with no abnormalities of chromosome no. 18.