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An experimental geneticist looks at catecholamine metabolism
Author(s) -
Shire J. G. M.
Publication year - 1981
Publication title -
clinical genetics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.543
H-Index - 102
eISSN - 1399-0004
pISSN - 0009-9163
DOI - 10.1111/j.1399-0004.1981.tb00739.x
Subject(s) - geneticist , biology , allele , phenotype , genetics , catecholamine , variation (astronomy) , genotype , genetic variation , evolutionary biology , gene , neuroscience , physics , astrophysics
The contributions of genetic variation, including that at unstable and duplicated loci, interactions between alleles at different loci and genotype‐environment interaction to observable phenotypic variation in experimental animals are discussed with particular reference to catecholamine metabolism. The possibilities and complexities involved in extrapolating to human populations, and to behavioural consequences of biochemical variation, are outlined.