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Study on segregation and risk for abnormal offspring in carriers of pericentric inversion of the (p11←q13) segment of chromosome 2
Author(s) -
Baccichetti Carlo,
Lenzini Elisabetta,
Pesericoi Andrea,
Tenconi Romano
Publication year - 1980
Publication title -
clinical genetics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.543
H-Index - 102
eISSN - 1399-0004
pISSN - 0009-9163
DOI - 10.1111/j.1399-0004.1980.tb01783.x
Subject(s) - chromosomal inversion , offspring , genetics , biology , chromosome , chromosome 9 , inversion (geology) , karyotype , gene , pregnancy , paleontology , structural basin
Pericentric inversion of chromosome 2 was detected in four unrelated families. All these inversions involved the segment p11←q13. The pedigree data are considered in comparison with other cases reported in the literature. Segregation data and possible reproductive failures are discussed.