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Prenatal diagnosis of severe congenital malformations associated with elevated amniotic fluid alpha–feto protein
Author(s) -
CHEMKE J.,
NlSANl R.,
KASSIF R.,
LANCET M.,
BEISER R.,
HURWITZ N.
Publication year - 1979
Publication title -
clinical genetics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.543
H-Index - 102
eISSN - 1399-0004
pISSN - 0009-9163
DOI - 10.1111/j.1399-0004.1979.tb01745.x
Subject(s) - amniotic fluid , prenatal diagnosis , medicine , alpha (finance) , obstetrics , fetus , amniocentesis , pregnancy , biology , genetics , surgery , construct validity , patient satisfaction
Two cases of severely malformed infants with abnormal fetal images on B–scan sonography and markedly elevated amniotic fluid AFP are presented. There was no evidence of neural tube anomalies. The importance of an amniocentesis and AFP in pregnancies with an abnormal fetal image on B–scan sonography is emphasized, taking into consideration that most pregnancies with elevated fluid AFP have serious fetal anomalies.