Premium
Genetic studies in a family with inverted nipples (mammillae invertita)
Author(s) -
Shafir R.,
Bonne–Tamir B.,
Ashbel S.,
Tsur H.,
Goodman R. M.
Publication year - 1979
Publication title -
clinical genetics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.543
H-Index - 102
eISSN - 1399-0004
pISSN - 0009-9163
DOI - 10.1111/j.1399-0004.1979.tb01744.x
Subject(s) - pedigree chart , genetics , family studies , gynecomastia , trait , brother , biology , medicine , gene , sociology , computer science , anthropology , programming language
A Jewish Sephardi family is reported in which 16 members are affected (15 females and 1 male) with inverted nipples. The one affected male and his brother also have gynecomastia. Under the assumption that this trait is transmitted as an autosomal dominant, linkage studies were done but were not revealing. Further family and investigative studies are needed in this disorder to understand better its pathogenesis and precise mode of genetic transmission.