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Down syndrome due to 21;21 translocation in a male twin
Author(s) -
Balfour Beverly,
Say Burhan,
Geffen William A.,
Morgan David G.,
Carpenter Nancy J.,
Munshi Gaurang
Publication year - 1979
Publication title -
clinical genetics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.543
H-Index - 102
eISSN - 1399-0004
pISSN - 0009-9163
DOI - 10.1111/j.1399-0004.1979.tb01345.x
Subject(s) - chromosomal translocation , crystal twinning , genetics , down syndrome , twin study , biology , medicine , gene , chemistry , crystallography , microstructure , heritability
A spontaneous 21;21 translocation resulting in features consistent with Down syndrome is reported in the first born of male fraternal twins. No history of twinning or chromosomal abnormalities in the family was noted. Any association between dizygous twinning and Down syndrome due to de novo translocation remains speculative until a sufficient pool of published data is available from study of such families.