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Chromosomal variants in mentally retarded and normal men
Author(s) -
Soudek D.,
Sroka Helena
Publication year - 1979
Publication title -
clinical genetics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.543
H-Index - 102
eISSN - 1399-0004
pISSN - 0009-9163
DOI - 10.1111/j.1399-0004.1979.tb00859.x
Subject(s) - mentally retarded , genetics , phenotype , biology , gene , psychology , developmental psychology
The possible phenotypic effect of chromosomal variants is as yet an unsolved problem. QM‐ and C‐banded chromosomes of 100 male patients with idiopathic mental retardation were compared with chromosomes of 100 Royal Military College cadets, as controls. Increased size of 9qh seems to be a factor with possible negative effects. 9qh– was found to be more common in the control sample. Another variant found more often in the retarded subjects was 16qh –. Increased frequencies of Yq+ or small inversions in chromosomes 3 and 9 were not found in the retarded.