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Ultrasonography for guidance of amniocentesis in genetic counseling
Author(s) -
Levine Sandra C.,
Filly Roy A.,
Golbus Mitchell S.
Publication year - 1978
Publication title -
clinical genetics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.543
H-Index - 102
eISSN - 1399-0004
pISSN - 0009-9163
DOI - 10.1111/j.1399-0004.1978.tb02118.x
Subject(s) - amniocentesis , medicine , amniotic fluid , ultrasonography , obstetrics , ultrasound , pregnancy , second trimester , gynecology , prenatal diagnosis , fetus , radiology , biology , genetics
The value of preliminary ultrasonography as a guide for amniocentesis in the early second trimester of pregnancy was prospectively evaluated. One hundred and fifty patients were alternately assigned to a control group or to an ultrasound group who underwent examination with a real‐time scanner immediately prior to amniocentesis. All amniotic fluid samples were assessed as to the presence of blood by: (1) visual observation during the amniocentesis; (2) appearance of the centrifugate; and (3) microscopic analysis. Ultrasonography did not reduce the failure rate, the incidence of multiple needle insertions, or the proportion of amniotic fluid samples containing blood.

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