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Caudal regression anomalad (sacral agenesis) in siblings
Author(s) -
Finer Neil N.,
Bowen Peter,
Dunbar Lawrence G.
Publication year - 1978
Publication title -
clinical genetics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.543
H-Index - 102
eISSN - 1399-0004
pISSN - 0009-9163
DOI - 10.1111/j.1399-0004.1978.tb01192.x
Subject(s) - agenesis , hypoplasia , regression , renal agenesis , biology , anatomy , medicine , genetics , psychology , psychoanalysis , kidney
Hypoplasia of the caudal end of the spine and associated anomalies were observed in two male siblings who also had congenital heart disease. The disorder has overlapping features with the VATER association and the caudal regression anomalad, and probably has a genetic basis, although the mode of inheritance is not clear.