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Colton blood groups: indication of linkage with the Kidd (Jk) system as support for assignment to chromosome 7
Author(s) -
Mohr Jan,
Eiberg Hans
Publication year - 1977
Publication title -
clinical genetics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.543
H-Index - 102
eISSN - 1399-0004
pISSN - 0009-9163
DOI - 10.1111/j.1399-0004.1977.tb01329.x
Subject(s) - monosomy , linkage (software) , genetics , chromosome , biology , genetic linkage , microbiology and biotechnology , karyotype , gene
A material of normal Danish families was tested for a number of genetic marker systems and analyzed for linkage. For the Colton‐Kidd relationship the lod score was + 2.57. The Kidd system has earlier been tentatively assigned to chromosome 7 (Shokeir et al. 1973). The present data therefore permit a tentative assignment to chromosome 7 of the Colton system as well. The data also suggest that the discovery by Chapelle et al. (1975) of a conjunction of monosomy for chromosome 7 in the bone marrow of certain leukemia patients and absence of Colton antigen from the red cells may now be interpreted as being connected with location on chromosome 7 of the Colton system.