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A family with syndactyly type II (synpolydactyly)
Author(s) -
Ridler M. A. C.,
Laxova Renate,
Dewhurst K.,
SaldañaGarcia P.
Publication year - 1977
Publication title -
clinical genetics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.543
H-Index - 102
eISSN - 1399-0004
pISSN - 0009-9163
DOI - 10.1111/j.1399-0004.1977.tb00929.x
Subject(s) - syndactyly , abo blood group system , genetics , biology , medicine
Syndactyly Type II is reported in eight members of a family in four generations. Affected individuals show two distinctive patterns of variation in the expression of the gene. Distortion of dermatoglyphic patterns is associated with the severe but not the mild manifestation of the malformation. The diagnostic significance of minimal features of the condition is discussed. Linkage data suggest that loci for Syndactyly II and for blood‐group antigens ABO, MNSs, P, Rh and Kell are not closely linked.