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Re‐evaluation of the effect of spray adhesives on human chromosomes
Author(s) -
Lubs H. A.,
Verma R. s.,
Summitt R. L.,
Hecht F.
Publication year - 1976
Publication title -
clinical genetics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.543
H-Index - 102
eISSN - 1399-0004
pISSN - 0009-9163
DOI - 10.1111/j.1399-0004.1976.tb01578.x
Subject(s) - adhesive , biology , andrology , medicine , chemistry , organic chemistry , layer (electronics)
The possible effects of spray adhesives on human chromosomes were re‐examined in several ways by three different laboratories. A total of 3,382 metaphases were analyzed in a blind‐coded fashion. The proportion of abnormal cells, including gaps, was similar in both the control (8.2%) and exposed (8.3%) samples. Our findings do not confirm the original investigation in which the proportion of abnormal cells was found to be significantly higher in the exposed group (8.99%) than in the control group (1.65%). In the earlier study, however, blind‐coded slides were not employed. These and other studies show no positive evidence of an effect of spray adhesives on human chromosomes.