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A dominant syndrome of metacarpal and metatarsal asymmetry with tarsal and carpal fusions, syndactyly, articular dysplasia and platyspondyly *
Author(s) -
Christian J. c.,
Franken E. A.,
Lindeman J. P.,
Lindseth R. E.,
Reed T.,
Scott C. I.
Publication year - 1975
Publication title -
clinical genetics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.543
H-Index - 102
eISSN - 1399-0004
pISSN - 0009-9163
DOI - 10.1111/j.1399-0004.1975.tb01957.x
Subject(s) - syndactyly , anatomy , tarsal bone , medicine , metatarsal bones , carpal bones , dysplasia , brachydactyly , osteochondrodysplasia , phalanx , wrist , short stature , pathology , ankle
A mother and daughter with metacarpal and metatarsal asymmetry, tarsal and carpal fusions, long bone articular dysplasia and platyspondyly are reported as a possible autosomal dominant syndrome affecting skeletal development. The asymmetry of the second metacarpals is perhaps the most striking finding and resulted in a range of bone lengths in the two individuals from minus 6.3 to plus 3.7 standard deviations from the mean.