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A rapid micro culture method of chromosome preparations from fibroblasts and amniotic cells *
Author(s) -
Singh Surjit,
Willers Ingrid,
Schloot Werner,
Goedde H. Werner
Publication year - 1975
Publication title -
clinical genetics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.543
H-Index - 102
eISSN - 1399-0004
pISSN - 0009-9163
DOI - 10.1111/j.1399-0004.1975.tb01949.x
Subject(s) - amniotic fluid , prenatal diagnosis , chromosome , cytological techniques , andrology , microbiology and biotechnology , biology , fetus , chemistry , genetics , pathology , medicine , pregnancy , gene
A micromethod enabling the making of chromosome preparations from fibroblasts and amniotic cells cultured on surface‐treated Microtest II plates is presented. Preparations from each well contain sufficient metaphases to perform a reliable diagnosis. The potential for the use of this method in early prenatal diagnosis is discussed.