Premium
Hepatitis associated antigen and the ABO locus in Down's syndrome
Author(s) -
Rundle A. T.,
Atkin J.,
Sudell B.
Publication year - 1975
Publication title -
clinical genetics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.543
H-Index - 102
eISSN - 1399-0004
pISSN - 0009-9163
DOI - 10.1111/j.1399-0004.1975.tb01946.x
Subject(s) - abo blood group system , immunology , antigen , hemagglutination , medicine , hepatitis , hepatitis b , locus (genetics) , biology , genetics , gene
The recent observation by Arndt‐Hansen et al. (1974) of increased frequency of blood group A over group O in blood donors positive for the hepatitis associated antigen has been investigated in Down's syndrome, in order to establish if this could account for the increased frequency of the antigen in that syndrome. Seventy‐one of 227 subjects with Down's syndrome (31.3%) were found to be positive for the antigen by haemagglutination, and comparison of these with the HAA‐subjects failed to reveal any differences in the ABO blood groups.