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Serum esterases of Icelanders 1. A “silent” pseudocholinesterase gene in an icelandic family
Author(s) -
Arnason Alfred,
Jensson Olafur,
Gudmundsson Sigurdur
Publication year - 1975
Publication title -
clinical genetics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.543
H-Index - 102
eISSN - 1399-0004
pISSN - 0009-9163
DOI - 10.1111/j.1399-0004.1975.tb00349.x
Subject(s) - allele , genetics , icelandic , cousin , esterase , gene , cholinesterase , biology , allele frequency , gene family , enzyme , endocrinology , biochemistry , history , gene expression , philosophy , linguistics , archaeology
During an investigation of cousin marriages in Iceland, five brothers and sisters were found to be hornozygous for the “silent” allele of plasma cholinesterase. Clinical information on two family members is presented and discussed, and the possibility of the presence of a “nearly silent” plasma esterase allele, in one of the family units investigated, is suggested.