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An XYY baby with Prader syndrome
Author(s) -
Iinuma Kazuso,
Tanae Ayako,
Tanaka Goro
Publication year - 1974
Publication title -
clinical genetics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.543
H-Index - 102
eISSN - 1399-0004
pISSN - 0009-9163
DOI - 10.1111/j.1399-0004.1974.tb02093.x
Subject(s) - phenotype , sexual differentiation , endocrinology , autosomal recessive trait , biology , medicine , fetus , genetics , pregnancy , gene
A case of an XYY baby with Prader syndrome is described. Phenotypic sex reversal could be attributed to the well defined defect in androgen excretion from fetal testes, which is inherited as an autosomal recessive trait. Our case is thought to be the first XYY female, in which the causal defect of sex differentiation could be identified apart from the double Y condition.