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Dermatoglyphics in Down's syndrome IV. Evaluation of the use of dermatoglyphic discriminants after the topological classification of constituent characters
Author(s) -
Oorthuys Anna M. A.,
Doesburg Willem H.
Publication year - 1974
Publication title -
clinical genetics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.543
H-Index - 102
eISSN - 1399-0004
pISSN - 0009-9163
DOI - 10.1111/j.1399-0004.1974.tb01712.x
Subject(s) - dermatoglyphics , disadvantage , medicine , linear discriminant analysis , mathematics , dermatology , pediatrics , statistics , genetics , artificial intelligence , biology , computer science
The dermatoglyphic discriminants proposed by Penrose & Loesch were used for differentiation between samples of 183 patients with Down's syndrome and 125 controls. The discriminant weightings determined for our Dutch individuals did not deviate much from those determined by Penrose & Loesch for individuals in Great Britain. The estimated percentage of misclassification compares well with the same quantity calculated in the original papers. Moreover, since the method compares well with other known scoring methods, it can be used to advantage in cases of unknown or discrepant symptoms in a patient. The disadvantage of the method, for the confirmation of a clinical diagnosis of Down's syndrome, seems to be that it is rather laborious.