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Complex five‐break rearrangement
Author(s) -
Fitzgerald Margaret G.
Publication year - 1974
Publication title -
clinical genetics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.543
H-Index - 102
eISSN - 1399-0004
pISSN - 0009-9163
DOI - 10.1111/j.1399-0004.1974.tb01661.x
Subject(s) - chromosomal translocation , karyotype , chromosomal rearrangement , biology , genetics , chromosome , gene
Multiple developmental anomalies in a male infant were associated with morphological abnormalities of a No. 2 and a No. 3 chromosome. Banding studies revealed a complex rearrangement interpreted as a reciprocal translocation and an insertion following five breaks, with no apparent loss of chromosomal material. Karyotype: 46 , XY, t (2p‐; 3q+), i (2q+; 3p‐) nomp (not maternally or paternally inherited).