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A syndrome of polydactyly‐syndactyly and triphalangeal thumbs in three generations
Author(s) -
Yujnovsky Osvaldo,
Ayala Dante,
Vincitorio Angel,
Viale Hercules,
Sakati Nadia,
Nyhan William L.
Publication year - 1974
Publication title -
clinical genetics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.543
H-Index - 102
eISSN - 1399-0004
pISSN - 0009-9163
DOI - 10.1111/j.1399-0004.1974.tb00630.x
Subject(s) - syndactyly , polydactyly , anatomy , ectrodactyly , medicine , hypoplasia , dysostosis , congenital disease , ectodermal dysplasia , surgery , dermatology
A syndrome has been observed in four individuals in three generations in which there is polydactyly and syndactyly of the hands and feet and triphalangeal thumbs. The syndrome is characterized by an unusual malformation of the lower extremities, in which there is hypoplasia of the tibia and a large, curved fibula dislocated on the femur. The pattern of inheritance is consistent with the action of an autosomal dominant gene.