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The electrocardiogram and sex chromosome aneuploidy
Author(s) -
Price W. H.,
Lauder I. J.,
Wilson J.
Publication year - 1974
Publication title -
clinical genetics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.543
H-Index - 102
eISSN - 1399-0004
pISSN - 0009-9163
DOI - 10.1111/j.1399-0004.1974.tb00623.x
Subject(s) - karyotype , aneuploidy , x chromosome , intraventricular conduction , medicine , cardiology , conduction abnormalities , chromosome , electrocardiography , biology , genetics , gene
A further study of the electrocardiogram in patients with sex chromosome abnormalities who have no evidence of heart disease is described. It is confirmed that in 47, XYY males the atrioventricular conduction is delayed and that in 45, X females it is accelerated. In 47, XYY males there is also a higher than normal frequency of minor defects of intraventricular conduction. No significant deviation from normal was found in the electrocardiogram of men with a 47, XXY karyotype or in 47, XXX women. The significance of the finding is discussed.