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Genetic studies in a family with testicular feminization, haemophilia A and colour blindness
Author(s) -
Holmberg Lars
Publication year - 1972
Publication title -
clinical genetics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.543
H-Index - 102
eISSN - 1399-0004
pISSN - 0009-9163
DOI - 10.1111/j.1399-0004.1972.tb04273.x
Subject(s) - haemophilia a , genetics , testicular feminization , genetic linkage , inheritance (genetic algorithm) , biology , blindness , genetic counseling , haemophilia , non mendelian inheritance , linkage (software) , medicine , gene , cancer , optometry , androgen receptor , prostate cancer , mitochondrial dna
The mode of inheritance of the syndrome of testicular feminization (tf) is not clear. Linkage studies to date have been inconclusive. A unique family with tf and with haemophilia A and deutan colour blindness is reported. Despite information about three X‐chromosomal and several autosomal genetic markers, no definite evidence in favour of X‐chromosomal or autosomal inheritance can be presented.