Premium
PEDIG ‐ A computer program for calculation of genotype probabilities using phenotype information
Author(s) -
Heuch Ivar,
Li Francis H. F.
Publication year - 1972
Publication title -
clinical genetics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.543
H-Index - 102
eISSN - 1399-0004
pISSN - 0009-9163
DOI - 10.1111/j.1399-0004.1972.tb01488.x
Subject(s) - computer program , genetics , inheritance (genetic algorithm) , phenotype , locus (genetics) , genotype , computer science , biology , computational biology , gene , programming language
A program has been constructed for computer calculation of the probabilities of certain genotypes for a given propositus, conditional on the phenotype information in a pedigree without loops. The program can be applied directly for one autosomal or sex‐linked locus, but is in fact more general and can easily be adapted to handle any situation with a completely known mode of inheritance.