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Precipitating factors against chicken proteins in patients with Down's syndrome
Author(s) -
Adinolfi M.,
Gilligan B.
Publication year - 1970
Publication title -
clinical genetics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.543
H-Index - 102
eISSN - 1399-0004
pISSN - 0009-9163
DOI - 10.1111/j.1399-0004.1970.tb01630.x
Subject(s) - agar gel , antibody , antigen , medicine , globulin , blood proteins , mentally retarded , gamma globulin , agar , endocrinology , immunology , biology , genetics , microbiology and biotechnology , psychology , bacteria , developmental psychology
Precipitating factors against chicken serum proteins detected by double diffusion in agar gel were observed in 40 % of D.S. patients studied. The precipitating factors were found to be associated with γ G globulins. Similar factors were absent in groups of normal children, mentally retarded subjects, and parents and siblings of the D.S. patients. No association was found between the precipitating factors and the presence of Pe antibodies or Au‐SH antigens.