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Co‐factor‐enhanced food allergy
Author(s) -
Cardona V.,
Luengo O.,
Garriga T.,
LabradorHorrillo M.,
SalaCunill A.,
Izquierdo A.,
Soto L.,
Guilarte M.
Publication year - 2012
Publication title -
allergy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.363
H-Index - 173
eISSN - 1398-9995
pISSN - 0105-4538
DOI - 10.1111/j.1398-9995.2012.02877.x.
Subject(s) - food allergy , culprit , medicine , allergy , allergen , anaphylaxis , oral allergy syndrome , food allergens , dermatology , risk factor , alcohol , immunology , biology , biochemistry , myocardial infarction
Background Alcohol, exercise or non‐steroidal anti‐inflamatory drugs ( NSAID ) are frequently mentioned as amplifiers of food allergic reactions but only individual cases or small series have been previously published. Methods Descriptive study including 74 cases of suspected co‐factor enhanced food allergy, assessed by skin‐prick tests, specific I g E and oral challenges. Results Anaphylaxis accounted for 85.1% of reactions. In 99% of cases culprit food allergens were plant‐derived, mainly vegetables and cereals. NSAID were involved in 58%, exercise in 52.7% and alcohol in 12.2%. Lipid transfer protein was the most frequently involved allergen. Conclusions C o‐factor enhanced food allergy should be considered when assessing food, alcohol, exercise and NSAID allergic reactions.