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Effect of parasite infection on allergic disease
Author(s) -
Capron M.
Publication year - 2011
Publication title -
allergy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.363
H-Index - 173
eISSN - 1398-9995
pISSN - 0105-4538
DOI - 10.1111/j.1398-9995.2011.02624.x
Subject(s) - immunology , helminths , allergy , biology , helminth infections , disease , helminthiasis , immune system , adaptation (eye) , acquired immune system , hygiene hypothesis , medicine , pathology , neuroscience
To cite this article: Capron M. The effect of parasite infection on allergic disease. Allergy 2011; 66 (Suppl. 95): 16–18. Abstract Vertebrates and helminths have co‐evolved for 500 million years, developing mutual adaptation mechanisms between parasites and hosts. Today, however, helminth diseases are among the most neglected communicable diseases. Epidemiological evidence shows that exposure to helminth parasites is inversely correlated with allergy incidence, and helminths induce immune hyporeactivity in both the innate and adaptive systems. The mechanisms include parasite‐derived regulatory molecules, the study of which opens new avenues for the control of allergic and autoimmune diseases.