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Impact of allergic rhinitis on asthma in children: effects on bronchodilation test
Author(s) -
Capasso M.,
Varricchio A.,
Ciprandi G.
Publication year - 2010
Publication title -
allergy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.363
H-Index - 173
eISSN - 1398-9995
pISSN - 0105-4538
DOI - 10.1111/j.1398-9995.2009.02168.x
Subject(s) - bronchodilation , medicine , spirometry , asthma , allergy , basal (medicine) , immunology , bronchodilator , insulin
To cite this article: Capasso M, Varricchio A, Ciprandi G. Impact of allergic rhinitis on asthma in children: effects on bronchodilation test. Allergy 2010; 65 : 264–268 DOI: 10.1111/j.1398‐9995.2009.02168.x. Abstract Background: Relevant relationship exists between upper and lower airways. Bronchial obstruction is a paramount feature of asthma and its reversibility is considered a diagnostic step for asthma diagnosis. Objective: This study aimed at evaluating a large group of children with allergic rhinitis alone for investigating the degree of brochodilation and possible factors related to it. Methods: Two hundred patients with allergic rhinitis and 150 normal subjects were consecutively evaluated. Clinical examination, skin prick test, spirometry, and bronchodilation test were performed in all patients. Results: Rhinitics showed a significant FEV 1 increase after bronchodilation test ( P < 0.0001) in comparison both to basal values and to controls’ levels. More than 20% of rhinitics had reversibility (≥12% basal levels). Patients with reversibility had lower FEV 1 levels, longer rhinitis duration, and perennial allergy. Conclusion: This study highlights the close link between upper and lower airways and the relevance of performing bronchodilation test in patients with allergic rhinitis and these characteristics.