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Allergic hypersensitivity to topical and systemic corticosteroids: a review
Author(s) -
Baeck M.,
Marot L.,
Nicolas J.F.,
Pilette C.,
Tennstedt D.,
Goossens A.
Publication year - 2009
Publication title -
allergy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.363
H-Index - 173
eISSN - 1398-9995
pISSN - 0105-4538
DOI - 10.1111/j.1398-9995.2009.02038.x
Subject(s) - medicine , immunology , allergy , dermatology , adrenal cortex hormones , hypersensitivity reaction
Corticosteroids, which are potent anti‐inflammatory and immunomodulator agents used in the treatment of various inflammatory diseases including allergic diseases, can in some cases produce immediate or delayed hypersensitivity reactions. This review summarizes the epidemiological and clinical characteristics of such reactions, including related diagnostic issues. It also presents a detailed analysis of the proposed immunological mechanisms including underlying cross‐reactions.