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The rise of the phoenix: the expanding role of the eosinophil in health and disease
Author(s) -
Adamko D. J.,
Odemuyiwa S. O.,
Vethanayagam D.,
Moqbel R.
Publication year - 2005
Publication title -
allergy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.363
H-Index - 173
eISSN - 1398-9995
pISSN - 0105-4538
DOI - 10.1111/j.1398-9995.2005.00676.x
Subject(s) - eosinophil , immunology , disease , asthma , effector , immune system , biology , medicine , pathology
We have entered a new phase in the evolution of our understanding of the role of the eosinophil with a greater appreciation of novel potential functions that may be ascribed to this enigmatic cell type. This review not only provides an update to our current understanding of the various immunobiological roles for the eosinophil, but also attracts attention to some novel observations predicting functions beyond its putative effector role. These observations include the intriguing possibility that the eosinophil may posses the capacity to regulate the immune and inflammatory responses in diseases such as asthma.