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Interferon‐alpha treatment for severe atopic dermatitis
Author(s) -
Kimata H.,
Akiyama Y.,
Kubota M.,
Furusho K.
Publication year - 1995
Publication title -
allergy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.363
H-Index - 173
eISSN - 1398-9995
pISSN - 0105-4538
DOI - 10.1111/j.1398-9995.1995.tb05059.x
Subject(s) - medicine , atopic dermatitis , immunoglobulin e , alpha interferon , immunology , chronic hepatitis , interferon alfa , alpha (finance) , interferon , peripheral blood mononuclear cell , in vitro , antibody , virus , biology , biochemistry , construct validity , nursing , patient satisfaction
Patients with both severe atopic dermatitis (AD) and chronic myeloid leukemia, chronic hepatitis B, or chronic hepatitis C were treated with interferon‐alpha (IFN‐α). IFN‐α treatment improved AD. Moreover, there were also significant decreases in serum IgE and IgG4 levels and in in vitro spontaneous IgE and IgG4 production by patients' mononuclear cells.