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Levels of soluble ICAM‐1 in atopic dermatitis A new marker for monitoring the clinical activity?
Author(s) -
Wüthrich B.,
JollerJemelka H.,
Kägi M.K.
Publication year - 1995
Publication title -
allergy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.363
H-Index - 173
eISSN - 1398-9995
pISSN - 0105-4538
DOI - 10.1111/j.1398-9995.1995.tb02488.x
Subject(s) - atopic dermatitis , medicine , exacerbation , eosinophil cationic protein , atopy , intercellular adhesion molecule 1 , immunology , interleukin , allergy , cell adhesion molecule , asthma , cytokine , eosinophil
Levels of soluble intercellular adhesion molecule‐1 (sICAM‐1) were measured in sera from patients with an acute exacerbation of their atopic dermatitis (AD) ( n = 16) on admission to and discharge from our department of dermatology. At admission, the sICAM‐1 levels in sera from patients with AD were slightly higher than those of the blood donors ( n = 100) and dropped at discharge significantly ( P = 0.014) after improvement of the skin conditions. Therefore, sICAM‐1 may be, together with soluble interleukin‐2 receptor (sIL‐2), eosinophilic cationic protein (ECP), and CD14, another marker for monitoring AD.