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Sensitivity to tomato and peanut allergens in children monosensitized to grass pollen
Author(s) -
Martino M.,
Novembre E.,
Cozza G.,
Marco A.,
Bonazza P.,
Vierucci A.
Publication year - 1988
Publication title -
allergy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.363
H-Index - 173
eISSN - 1398-9995
pISSN - 0105-4538
DOI - 10.1111/j.1398-9995.1988.tb00420.x
Subject(s) - provocation test , pollen , allergy , medicine , nasal provocation test , oral allergy syndrome , immunology , immunoglobulin e , allergen , food allergy , angioedema , intoxicative inhalant , radioallergosorbent test , dermatology , biology , botany , pathology , toxicology , alternative medicine , antibody
Possible associations between allergy to grass pollen and positive skin tests to food allergens were studied in 102 children monosensitized (as to inhalant allergens) to grass pollen, and in 117 children monosensitized (as to inhalant allergens) to Dermatophagoides . Thirty‐two foods were tested by an epicutaneous method. Positive skin tests to food allergens were more frequent in children with allergy to grass pollen (59.8%) than in children with allergy to Dermatophagoides (9.4%). A considerably high frequency of positive reactions to tomato (39.2%), peanut (22,5%), green pea (13.7%), and wheat (11.7%) was observed in children with allergy to grass pollen. Positive skin tests to peanut closely correlated with positive RAST results and nasal provocation tests, whereas in children with skin test positivity to tomato a close correlation with nasal provocation tests but a 45 % correlation with a positive RAST result were observed. RAST inhibition experiments were carried out, and the results may suggest the presence of cross‐reacting IgE to grass pollen, tomato, and peanut antigens. Clinical implications of these findings are discussed in the light of histories of food hypersensitivity, urticaria‐angioedema, and atopic dermatitis in children with allergy to grass pollen.