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Sustained‐Release Terbutaline in Nocturnal Asthma
Author(s) -
Westermann C. J. J.,
Weelden B. M.van,
Laros C. D.
Publication year - 1986
Publication title -
allergy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.363
H-Index - 173
eISSN - 1398-9995
pISSN - 0105-4538
DOI - 10.1111/j.1398-9995.1986.tb02034.x
Subject(s) - evening , terbutaline , morning , medicine , placebo , asthma , nocturnal , anesthesia , physics , alternative medicine , pathology , astronomy
Fifteen adult patients with nocturnal asthma entered a double blind study. They received single evening dose of one sustained‐release (SR) terbutaline tablet a 7.5 mg or an identical placebo tablet for 1 week, each in a randomised cross‐over fashion in addition to their usual medication. In the 12 evaluated patients there was no change in evening PEF but a significant improvement in morning PEF P < 0.05) and in overnight fall of PEF ( P < 0.01) on active treatment. Symptoms improved by both placebo and active medication. Three patients experienced tremor as a side effect. A single evening dose of SR‐terbutaline can be of help in nocturnal asthma.