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Simplification of Inhalation Therapy in Asthmatic children
Author(s) -
Pedersen S.,
Steffensen G.
Publication year - 1986
Publication title -
allergy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.363
H-Index - 173
eISSN - 1398-9995
pISSN - 0105-4538
DOI - 10.1111/j.1398-9995.1986.tb02032.x
Subject(s) - inhalation , medicine , asthma , intensive care medicine , pediatrics , anesthesia , immunology
In a placebo‐controlled double blind cross‐over study of 3 × 3 weeks' duration the effectiveness of a new set of simple instructions for the use of spacer aerosols was compared with that of the rather complicated manufacturer's instructions in the daily treatment of 22 children with severe asthma. All children received inhaled budesonide and terbutaline at the lowest dose possible for satisfactory symptom control. Both the simple and complicated regimes were significantly better than placebo ( P < 0.01), but there was no indication that the complicated regime was superior to the simple regime. On the contrary, the children used significantly more rescue terbutaline and experienced more day time symptoms when treated according to the complicated regime ( P < 0.01). 19 of 21 children who completed the study preferred to use the simple regime ( P < 0.01). It is concluded that conclusions for the use of spacer aerosols should be substantially simplified and that conclusions from laboratory studies should be tested in the day‐to‐day of asthmatics before these aerosols become widely used.