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Chewing‐Gum Preservative Induced Toxidermic Vasculitis
Author(s) -
MoneretVautrin D. A.,
Faure G.,
Bene M. C.
Publication year - 1986
Publication title -
allergy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.363
H-Index - 173
eISSN - 1398-9995
pISSN - 0105-4538
DOI - 10.1111/j.1398-9995.1986.tb00342.x
Subject(s) - medicine , provocation test , vasculitis , dermatology , chewing gum , menthol , lesion , dentistry , surgery , food science , pathology , chemistry , alternative medicine , disease , organic chemistry
This paper reports the case of a young female patient who presented with a cutaneous urticarial disseminated eruption. Drug‐induced side effects were eliminated, and the only recent dietary change was the regular use of chewing‐gums containing chlorophylla (E140), menthol and BHT (butylhydroxytoluene). Immunohistological analysis of a cutaneous lesion revealed signs of vasculitis. Within 1 week after stopping chewing gum, the eruption subsided. Oral provocation tests at 4‐day intervals confirmed the responsibility of BHT by the reinduction of the cutaneous signs after a few hours.