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A New, Purified Dermatophagoides farinae Allergen Preparation
Author(s) -
Moxnes A.,
Dale S.,
Andrew E.,
Halvorsen R.
Publication year - 1984
Publication title -
allergy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.363
H-Index - 173
eISSN - 1398-9995
pISSN - 0105-4538
DOI - 10.1111/j.1398-9995.1984.tb01951.x
Subject(s) - allergen , radioallergosorbent test , house dust mite , chromatography , mite , skin test , pyroglyphidae , chemistry , immunology , allergy , medicine , biology , pathology , tuberculosis , botany
A purified, standardized and characterized allergen preparation of the house dust mite Dermatophagoides farinae (Df) was evaluated by skin prick test (SPT) and radioallergosorbent test (RAST) in 88 subjects. Skin reactions to the purified Df preparation and a corresponding crude Df preparation were compared. SPT was also performed with a crude Dermatophagoides pteronyssinus (Dpt) preparation to compare reactions obtained with the two mite preparations. By SPT the purified Df allergen preparation was representative of the crude Df preparation ( r = 0.78) and the correlation between skin reactions to Df and Dpt was high ( r = 0.78). The concordance between results obtained with RAST and SPT techniques with the purified Df preparation was high (84%). The purified D. farinae preparation was well tolerated and is well suited for SPT.