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Antigenic/Allergenic Composition of Poodle/Alsatian Dandruff Extract
Author(s) -
Uhlin T.,
Reuterby J.,
Einarsson R.
Publication year - 1984
Publication title -
allergy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.363
H-Index - 173
eISSN - 1398-9995
pISSN - 0105-4538
DOI - 10.1111/j.1398-9995.1984.tb01944.x
Subject(s) - dandruff , medicine , dander , immunoelectrophoresis , antigen , immunodiffusion , immunology , allergy , pathology , allergen , shampoo
Poodle and Alsatian dog dandruff extracts were characterized by crossed immunoelectrophoresis (CIE) and crossed radioimmunoelectrophoresis (CRIE) using sera from 24 individuals clinically sensitive to dogs. By using a system with intermediate gel in immunoelectrophoresis, the content of dander‐specific and serum‐specific allergens was established. 29 antigens (18 dander‐specific and 11 serum‐specific) were identified in the mixed breed Poodle/Alsation dandruff extract. Of these, 24 antigens were radiostained in CRIE. 16 allergens were dander specific and the remaining eight were serum specific. Positive dog dander RAST (e5 and Poodle/Alsatian dandruff extract) results were observed in the tested dog hypersensitive subjects. Our results suggest that the mixture of Poodle/Alsatian dandruff extract may be a suitable preparation for the diagnosis and treatment of dog allergy.