Premium
Increased IgG Fc and C3 Rosette‐Forming Capacity of Granulocytes from Patients with Psoriasis
Author(s) -
Csató Miklós,
Kabók Zita,
Dobozy Attila
Publication year - 1984
Publication title -
allergy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.363
H-Index - 173
eISSN - 1398-9995
pISSN - 0105-4538
DOI - 10.1111/j.1398-9995.1984.tb01935.x
Subject(s) - psoriasis , rosette (schizont appearance) , immunology , rosette formation , antibody , receptor , granulocyte , fc receptor , medicine
In the present work the proportions of IgG Fc and C3 rosette‐forming granulocytes were studied in patients with severe psoriasis. The percentages of erythrocyte‐antibody and C3 rosette‐forming granulocytes from psoriasis patients were significantly higher than those of healthy individuals. Sera from patients with psoriasis did not influence the rosette formation by granulocytes from healthy persons. The increased IgC Ft and C3 receptor activities of granulocytes in psoriasis may account for the hyperactivity of these cells enhancing the susceptibility of the polymorphonuclears for at least some naturally occurring stimuli.